返回首页 | 山大基础医学院

 

师资队伍 当前位置: 网站首页 > 学术力量 > 师资队伍 > 正文  
王晓
作者:  来源:  发布时间:2017年03月21日 15:47  浏览次数:

王晓,医学博士,副主任医师,硕士研究生导师。山东省抗癌协会肿瘤病理分会消化学组副组长,中华医学会病理学分会消化学组委员,中国抗癌协会病理专委会食管癌学组委员。擅长消化系统疾病(尤其是消化道早癌)的病理诊断。曾赴澳大利亚昆士兰大学癌症中心及日本东京顺天堂医院研修。主持国家自然科学基金、省面上基金等课题7项,以第一作者和通讯作者发表SCI论文9篇。


近期发表的论文:

1. Juan Liu, Xiao Wang, Gengyin Zhou, Hong Wang, Lei Xiang, Yizhe Cheng, Wenjun Liu, Yan Wang, Jihui Jia and Weiming Zhao.Cancerous Inhibitor of Protein Phosphatase 2A Is Overexpressed in Cervical Cancer and Upregulated by Human Papillomavirus 16 E7 Oncoprotein. Gynecol Oncol,2011.08, 122(2):430-6.并列第一作者。

2. Wang X, Liu J, Zhao WM, Zhao KN.Translational comparison of HPV58 long and short L1 mRNAs in yeast (Saccharomyces cerevisiae) cell-free system. J Biosci Bioeng. 2010 Jul;110(1):58-65. Epub 2010 Feb 20.

3. Xiao Wang, Juan Liu, Wei Ming Zhao and Kong-Nan Zhao. Expression of HPV 58 long and short L1 capsid proteins in primary mouse keratinocyte cultures. Protein Peptide Letters,2009;16(1):65-74.

4. Xiao Wang, Juan Liu, Yan Zheng, Jing Li, Hong Wang, Yabin Zhou, Mei Qi, Han Yu, Wei Tang, Weiming Zhao. An optimized yeast cell-free lysate system: Sufficient for the translation of human papillomavirus 58 L1 Mrna and the assembly of virus-like particles. Journal of Bioscience and Bioengineering, 2008 Jul;106(1):8-15.

5. Xiao Wang, Bo Li, and Kong-Nan Zhao. Differential expression of papillomavirus L1 proteins encoded by authentic and codon modified L1 genes in methylcellulose-treated mouse keratinocytes,Virology Journal, 2007 Nov 25;4:127.

6. Bo Li, Xiao Wang, and Kong-Nan Zhao. Up-regulated expression of Sp1 protein coincident with a viral protein in human and mouse differentiating keratinocytes may acts as a cell differentiation marker. Differentiation, 2008 Dec, 76(10):1068-1080.

7. Jing Li, Xiao Wang, Juan Liu, Hong Wang, Xiaoli Zhang, Wei Tang, Yundong Sun, Xin Wang, Xiuping Yu, and Weiming Zhao* .Replication and transcription of human papillomavirus type 58 genome in Saccharomyces cerevisiae. Virology Journal, 2010 Dec 25;4:127.

8. Wenyi Gu, Jianmin Ding, Xiao Wang, Rachel L. de Kluyver, Nicholas A. Saunders, Ian H. Frazer, and Kong-Nan Zhao. Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiation. Nucleic Acids Research, 2007;35(14):4820-32.

9. Sun Y, Zhang T, Gao P, Meng B, Gao Y, Wang X, Zhang J, Wang H, Wu X, Zheng W, Zhou G. Targeting glucosylceramide synthase downregulates expression of the multidrug resistance gene MDR1 and sensitizes breast carcinoma cells to anticancer drugs. Breast Cancer Res Treat, (2009) Aug 20. [Epub ahead of print].

10. 国家发明专利(第二位):HPV基因酵母体外翻译系统的建立(已授权),申请号:200710015953.0


承担课题情况:

1. 新型致癌因子CIP2A在HPV致宫颈癌发生发展中的作用机制的初步研究,国家自然科学青年基金,项目负责人,2011.01-2013.12,20万

2. 宫颈癌中新型致癌蛋白CIP2A与HPV E6 E7相互作用的研究,中国博士后面上基金(一等奖),项目负责人,2010.01-2012.01,5万

3. 新型致癌因子CIP2A在HPV致宫颈癌发生发展中的作用机制的初步研究,山东大学自主创新基金,项目负责人,2010.01-2013.01,10万

4. 新型致癌因子CIP2A促进宫颈腺癌原发性耐药的机制研究,山东省自然科学基金青年基金,项目负责人,2011年7月到2014年7月,4万

 
上一条:吴晓娟
下一条:张晓芳

关闭


 
地址:山东省济南市文化西路44号 山东大学基础医学院医病理学系/山东大学病理中心  邮编:250012
版权所有:山东大学基础医学院医病理学系/山东大学病理中心 Copyrights © 2017 All Rights Reserved